Project Publications

Publications


High-Efficiency Trifluoromethyl-Methionine Incorporation into Cyclophilin A by Cell-Free Synthesis for 19F NMR Studies
​Dr. Wenkai Zhu, Christina M. Monnie, Kristīne Kitoka, Prof. Angela M. Gronenborn: High-Efficiency Trifluoromethyl-Methionine Incorporation into Cyclophilin A by Cell-Free Synthesis for 19F NMR Studies, Angewandte Chemie (Wiley-VCH), 2025, Volume 64, issue 7, ISSN: 1433-7851 Online ISSN: 1521-3773
https://doi.org/10.1002/anie.202419709


Harnessing the Power of 19F NMR for Characterizing Dimerization and Ligand Binding of 14-3-3 Proteins
Alexandra Náplavová, Aneta Kozeleková, Radek Crha, Angela M. Gronenborn, Jozef Hritz,
Harnessing the power of 19F NMR for characterizing dimerization and ligand binding of 14-3-3 proteins,
International Journal of Biological Macromolecules, Volume 305, Part 2, 2025, 141253, ISSN 0141-8130,
https://doi.org/10.1016/j.ijbiomac.2025.141253


Acidification of Phosphate Buffered Saline
Lukáš Veselý, Susrisweta Behera, Radim Štůsek, David Mužík, Dominik Heger
International Journal of Pharmaceutics
>>> recently published


Deciphering Opening Mechanisms of 14-3-3 Proteins
Exequiel E. Barrera, Rostislav Skrabana, Diego M. Bustos. Deciphering opening mechanisms of 14-3-3 proteins. Protein Science, 2025. Vol. 34, Issue 4. 
https://doi.org/10.1002/pro.70108


Disruption of Extracellular Matrix and Perineuronal Nets Modulates Extracellular Space Volume and Geometry
Eva Syková, Ivan Voříšek, Zenon Starčuk, Jiří Kratochvíla, Iveta Pavlova, Yuki Ichikawa, Jessica C. F. Kwok, Eva Kmoníčková, Svitlana Myronchenko, Tomáš Hromádka, Tomáš Smolek, Martin Avila, Neha Basheer and Norbert Žilka. Journal of Neuroscience 19 February 2025, 45 (8) e0517242024; DOI: 10.1523/JNEUROSCI.0517-24.2024


Characterization of multiple binding sites on microtubule associated protein 2c recognized by dimeric and monomeric 14-3-3ζ
JANSEN, Séverine, Subhash NARASIMHAN, Paula Cabre FERNANDEZ, Lucia IĽKOVIČOVA, Aneta KOZELEKOVA, Katerina KRÁLOVA, Jozef HRITZ a Lukáš ŽÍDEK (2025). Characterization of multiple binding sites on microtubule associated protein 2c recognized by dimeric and monomeric 14-3-3ζ. The FEBS Journal, 2025, 1742-464X. http://dx.doi.org/10.1111/febs.17405


Structures of oligomeric states of tau protein, amyloid-β, α-synuclein and prion protein implicated in Alzheimer's disease, Parkinson's disease and prionopathies
Cehlar, O., Njemoga, S., Horvath, M., Cizmazia, E., Bednarikova, Z., & Barrera, E. E. (2024). Structures of Oligomeric States of Tau Protein, Amyloid-β, α-Synuclein and Prion Protein Implicated in Alzheimer’s Disease, Parkinson’s Disease and Prionopathies. International Journal of Molecular Sciences, 25(23), 13049. https://doi.org/10.3390/ijms252313049


TLR4-mediated chronic neuroinflammation has no effect on tangle pathology in a tauopathy mouse model
Basheer N, Muhammadi MK, Freites CL, Avila M, Momand MUD, Hryntsova N, Smolek T, Katina S and Zilka N (2024) TLR4-mediated chronic neuroinflammation has no effect on tangle pathology in a tauopathy mouse model. Front. Aging Neurosci. 16:1468602. doi: 10.3389/fnagi.2024.1468602


​Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models
Basheer, N., Buee, L., Brion, JP. et al. Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models. acta neuropathol commun 12, 52 (2024). https://doi.org/10.1186/s40478-024-01748-5


Hiding in plain sight: Complex interaction patterns between Tau and 14-3-3ζ protein variants

Radek Crha, Aneta Kozeleková, Alena Hofrová, Lucia Iľkovičová, Norbert Gašparik, Pavel Kadeřávek, Jozef Hritz. International Journal of Biological Macromolecules, Volume 266, Part 2, 2024,130802, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2024.130802.


NMR Studies of Tau Protein in Tauopathies
Kitoka K., Skrabana R., Gašparik N., Hritz J., Jaudzems K. NMR Studies of Tau Protein in Tauopathies. Front. Mol. Biosci. 2021, 8:761227; doi: 10.3389/fmolb.2021.761227


dGAE(297-391) Tau Fragment Promotes Formation of Chronic Traumatic Encephalopathy-Like Tau Filaments

Kristine Kitoka, Alons Lends, Gytis Kucinskas, Anna Lina Bula, Lukas Krasauskas, Vytautas Smirnovas, Monika Zilkova, Branislav Kovacech, Rostislav Skrabana, Jozef Hritz, Kristaps Jaudzems: dGAE(297-391) Tau Fragment Promotes Formation of Chronic Traumatic Encephalopathy-Like Tau Filaments, Angewandte Chemie (Wiley-VCH), 2024, https://doi.org/10.1002/ange.202407821


​This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 873127 – InterTAU.

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